400-921-8278
Catalog_no | ADMC0154 |
Product_name | NVP-BEZ235 |
Category | 抑制剂与激动剂 |
Size | 50mg/100mg |
Price | 560.00/880.00 |
Specificity | Target: PI3K. Fields: BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM. |
Dilution | IC50: 4 nM (p110α), 5 nM (p110γ), 7 nM (p110δ), 75 nM (p110β), 6 nM (mTOR)[1] |
Purification | >98% |
Concentration | 靶点:PI3K;IC50: 4 nM (p110α), 5 nM (p110γ), 7 nM (p110δ), 75 nM (p110β), 6 nM (mTOR)[1] |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | BEZ235 |
Observed_band | 469.55 |
Notes | BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM. |
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